One area that’s especially difficult to treat is laugh lines. As skin loses elasticity with age, the lines that run from the sides of your nose toward the corners of your mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) appear more noticeable.

What are Restylane® Refyne and Defyne?

Restylane Refyne and Restylane Defyne are fillers intended to correct deeper wrinkles and folds in the laugh lines. As we age, our skin changes. Over time, the natural volume of youthful skin begins to diminish as wrinkles and folds form.
The same company that makes Refyne also makes Restylane, Sculptra, and Dysport, has just announced FDA approval of Restylane Refyne for the treatment of moderate wrinkles and folds from the nose to mouth.
Although there are other fillers on the market that can reduce the appearance of wrinkles, Refyne is meant to give a more natural-looking look. In fact, it is the only filler on the market that have been shown in clinical trials to help maintain natural movement and expressions.
An injection specialist at Dermacare in the Phoenix area says, “I’ve been monitoring the results that [Refyne] have been getting in other countries and couldn’t wait for it to make it to the US. It’s finally here and I couldn’t be more excited. Refyne gives some of the most natural results you can get from fillers. They help smooth away hard to treat laugh lines which are the wrinkles and folds at the sides of your nose and run down toward the corners of your mouth.”

Restylane Refyne is a specifically formulated hyaluronic acid dermal filler made with XpresHAn Technology™ that helps correct these lines for a more natural look to your face. The unique cross-linking of the gel in Restylane Refyne is also designed to help support your natural expression—for real-life results that help maintain natural movement when you’re smiling, frowning, and even puckering up.
Defyne is crafted with XpresHAn Technology™ to correct deepened lines. The unique cross-linking of the gel in Defyne is also designed to help support your facial expressions for natural-looking results that help maintain your natural movement.